allelic imbalance การใช้

• High density SNP arrays help scientists identify patterns of allelic imbalance.
• Copy-neutral LOH is a form of allelic imbalance.
• MIP, for instance, can be used to capture targets for SNPgenotyping, copy number variation or allelic imbalance studies, to name a few.
• It appears to be the mechanism targeting RASEF in uveal melanoma, and allelic imbalance at this locus supports a TSG role for the Ras and Ef-hand domain containing.
• They also accurately evaluated the allelic imbalance ( AI ), ratio of the transcripts produced by the single alleles, within a subgroup of genes involved in cell differentiation, adhesion, cell motility and muscle contraction identifying a unique transcriptomic and genomic signature in oral cancer patients.